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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study to Evaluate Immunotherapy for Non-Small Cell Lung Cancer

  2. A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers

    Scottsdale/Phoenix, AZ

  3. Immunological Consequences of COVID-19 Vaccination in Patients with Rheumatic Diseases

    Rochester, MN

  4. A Study of Selpercatinib to Treat Participants with RET-Mutant Medullary Thyroid Cancer

    Scottsdale/Phoenix, AZ

  5. A Single Patient Treatment Plan with Autologous Mesenchymal Stromal Cell Coated Fistula Plug in a Single Patient with Persistent Pouch-Vaginal Fistula

    Rochester, MN

  6. Treatment of Thumb Carpometacarpal (CMC) Arthritis Using Stablyx® CMC Arthroplasty System

    Rochester, MN

  7. A Phase I/II Study to Evaluate AZD5851 in GPC3+ Advanced/Recurrent Hepatocellular Carcinoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. A Study to Evaluate the Surgical Removal of Residual Brain Tumors Prior to Recurrence

    Rochester, MN

  9. Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic Cutaneous T Cell Lymphoma

    Scottsdale/Phoenix, AZ

  10. Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

    Rochester, MN

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