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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Probiotics Preventing Immune Checkpoint Inhibitor-Induced Colitis

    Jacksonville, FL

  2. A Study to Evaluate Dexamethasone in Reducing Everolimus-Induced Oral Stomatitis in Patients With Cancer

    La Crosse, WI, Eau Claire, WI, Rochester, MN

  3. A Study to Evaluate the Effectiveness, Safety, Pharmacokinetics and Pharmacodynamics of Idasanutlin Monotherapy in Participants With Hydroxyurea-Resistant/Intolerant Polycythemia Vera

    Scottsdale/Phoenix, AZ

  4. A Study Evaluating the Effectiveness of Oral Vismodegib in Various Histologic Subtypes of High Risk or Locally Advanced Basal Cell Carcinoma

    Jacksonville, FL

  5. A Study of Pembrolizumab Alone as Therapy for Metastatic Triple-Negative Breast Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. A Study to Detect Minimally-Invasive Barrett's Esophagus and Barrett's Esophagus Related Dysplasia/Carcinoma

    Rochester, MN, Jacksonville, FL, Austin, MN, Scottsdale/Phoenix, AZ

  7. A Study of Rucaparib Verses Physician's Choice of Therapy in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

    Scottsdale/Phoenix, AZ

  8. A Study of Whole-Brain Radiation Therapy with or without Avoiding the Hippocampus while Treating Patients with Limited or Extensive Stage Small Cell Lung Cancer

    La Crosse, WI, Albert Lea, MN, Eau Claire, WI, Mankato, MN, Rochester, MN

  9. Phase I Dose Escalation Study for BAY 1251152 in Patients With Advanced Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Study to Evaluate Safety and Preliminary Efficacy of MOR208 With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKi (COSMOS)

    Jacksonville, FL, Rochester, MN

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