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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 3921-3930 of 8059

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  • Locations: Rochester, MN
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  1. A Study of Mirvetuximab Soravtansine vs. Investigator's Choice of Chemotherapy in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression

    Rochester, MN, Jacksonville, FL, Scottsdale/Phoenix, AZ

  2. A Study to Evaluate Binimetinib in Combination with Encorafenib in Patients with Pancreatic Malignancies and a Somatic BRAFV600E Mutation

    Scottsdale/Phoenix, AZ, Rochester, MN

  3. Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

    Rochester, MN, Scottsdale/Phoenix, AZ

  4. A Study to Compare Saliva and Swab Specimens in Detection of COVID Severe Acute Respiratory Syndrome

    Rochester, MN

  5. A Study to Evaluate the Safety and Effectiveness of AK002 in Patients with Active Eosinophilic Gastritis

    Rochester, MN, Scottsdale/Phoenix, AZ

  6. Fecal Microbiota Transplantation for C. Difficile Infection in Solid Organ Transplant Recipients

    Rochester, MN

  7. Global Prospective Case Series Using a Single-Use Duodenoscope

    Rochester, MN

  8. Individualized Temozolomide in Treating Patients with Stage IV Melanoma that Cannot be Removed by Surgery

    Rochester, MN

  9. Aldesleukin Imaging in Viewing Tumor Growth in Patients With Stage IV Melanoma Receiving Ipilimumab Therapy

    Rochester, MN

  10. Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma

    Rochester, MN

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