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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 3471-3480 of 10862

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  1. A Study of the Effects of Menopause and Exercise on Blood Flow in Healthy Women

    Rochester, MN

  2. Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma

  3. Dosing Regimen of Eculizumab Added to Conventional Treatment in Positive Crossmatch Deceased Donor Kidney Transplant

    Rochester, MN

  4. Impact of Proteasome Inhibition on Anti-Donor HLA Antibody Production After Kidney Transplantation

    Rochester, MN

  5. Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III

    Jacksonville, FL

  6. Novel Support Options in Autologous Stem Cell Transplant for Multiple Myeloma

    Scottsdale/Phoenix, AZ

  7. Antiemetic Therapy With or Without Olanzapine in Preventing Chemotherapy-Induced Nausea and Vomiting in Patients With Cancer Receiving Highly Emetogenic Chemotherapy

    Rochester, MN

  8. A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas

    Jacksonville, FL, Rochester, MN

  9. An Efficacy and Safety Study of Gevokizumab in Treating Active Ulcers of Pyoderma Gangrenosum

    Scottsdale/Phoenix, AZ

  10. Evaluation of t-RFA and RF-TVA Prior to/Following Radiation Therapy to Treat Painful Metastatic Vertebral Body Tumor(s)

    Rochester, MN

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