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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study of the Presence of Viral Pathogens in Culture-Negative, Non-Specific Pleuritis

    Rochester, MN

  2. A Study of a Sleep Health ‘App’ to Help First-Time Users of Positive Airway Pressure Therapy for Sleep Apnea

    Scottsdale/Phoenix, AZ, Rochester, MN

  3. A Trial of Two Fixed Doses of ZX008 (Fenfluramine HCl) in Children and Young Adults With Dravet Syndrome

    Rochester, MN

  4. A Study of the Effectiveness and Safety of Vedolizumab Compared to Adalimumab for Participants with Ulcerative Colitis

    Rochester, MN

  5. Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery

    Rochester, MN, Scottsdale/Phoenix, AZ

  6. A Study of the GORE® TAG® Thoracic Branch Endoprosthesis for Treating Proximal Descending Thoracic Aortic Aneurysms

    Rochester, MN

  7. A Study of Tretinoin and Arsenic Trioxide in Treating Patients with Untreated Acute Promyelocytic Leukemia

  8. Short Versus Long Cephalomedullary Nailing of Pertrochanteric Hip Fractures: A Randomized Prospective Study

    Rochester, MN

  9. Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors

    Rochester, MN

  10. A Study of the Best Position for the Passive Driver (Vibration Transmitter) in Cardiac Magnetic Resonance Elastography (MRE)

    Rochester, MN

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