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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 2481-2490 of 10853

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  1. Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases

    La Crosse, WI, Albert Lea, MN, Eau Claire, WI, Mankato, MN, Rochester, MN, La Crosse, WI

  2. A Study to Evaluate a New Device for Increasing Accuracy and Efficiency of Image-Guided Stereo EEG Procedures

    Rochester, MN

  3. A Study To Evaluate the Effectiveness, Safety, And Tolerability of a Clostridium Difficile Vaccine In Adults 50 Years of Age and Older

    Rochester, MN

  4. Ultrasonic Energy for Pulmonary Artery Branch Sealing During VATS Lobectomy

  5. REDUCE LAP-HF TRIAL II

    Rochester, MN

  6. Assessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast Surgery

    Rochester, MN

  7. A Study to Assess the Efficacy and Safety of Risankizumab in Subjects With Moderately to Severely Active Crohn's Disease Who Failed Prior Biologic Treatment

    Rochester, MN, Rochester, MN

  8. Bariatric Surgery Versus Diet Alone in the Bile Acid Pathway and Weight Loss

    Rochester, MN

  9. New Technologies to Determine Carotid Plaque Vulnerability in Patients With Significant Carotid Plaques

    Rochester, MN

  10. A Study to Evaluate the Use of Adipose-derived Regenerative Cells in Bilateral Femoral Head Osteonecrosis

    Rochester, MN

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