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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study in People With Systemic Sclerosis to Test Whether BI 685509 Has an Effect on Lung Function and Other Systemic Sclerosis Symptoms

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. A Study to Evaluate the Efficacy and Safety of GSK3915393 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

    Jacksonville, FL, Rochester, MN

  3. A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (Meteoroid)

    Rochester, MN, Scottsdale/Phoenix, AZ

  4. Coronary Sinus Reducer For The Management Of Symptomatic Heart Failure

    Rochester, MN

  5. CJNJ-67652000 and Prednisone for the Treatment of Men With Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

    Jacksonville, FL, Rochester, MN, Scottsdale/Phoenix, AZ

  6. MUC1 Gene Expression

    Rochester, MN

  7. Droxidopa / Pyridostigmine in Orthostatic Hypotension

    Rochester, MN

  8. VE303 for Prevention of Recurrent Clostridioides Difficile Infection (RESTORATiVE303)

    Scottsdale/Phoenix, AZ

  9. Combination Chemotherapy or 90-Yttrium Ibritumomab Tiuxetan and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Relapsed Diffuse Large B-cell Non-Hodgkin Lymphoma

  10. A Study to Evaluate the Use of Nivolumab and Pomalidomide Combination for Relapsed/Refractory Primary Central Nervous System Lymphoma and Primary Vitreoretinal Lymphoma

    Jacksonville, FL, Rochester, MN

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