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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Agili-C™ Implant Performance Evaluation

    Rochester, MN

  2. Monitoring Neoadjuvant Chemotherapy Of Breast Cancer Using 3D Subharmonic Aided Pressure Estimation

    Rochester, MN

  3. Testing An Active Form Of Tamoxifen (4-hydroxytamoxifen) Delivered Through The Breast Skin To Control Ductal Carcinoma In Situ (DCIS) Of The Breast

  4. COVFIS-HOME: COVID-19 Pilot Study of Fisetin to Alleviate Dysfunction and Decrease Complications

    Rochester, MN

  5. Development of a Practical, Minimally Invasive Seizure Gauge

    Rochester, MN

  6. A Study of the Thalamus Using Deep Electrode EEG to Better Understand its Participation in the Beginning or Spreading of Seizures

    Rochester, MN

  7. Treating Epilepsy With Transcranial Direct Current Stimulation

    Rochester, MN

  8. A Study to Assess Neuroinflammation in Epileptic Tissue Immediately Prior to Surgical Resection Using Intraoperative Brain Microdialysis

    Rochester, MN

  9. Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection

    Rochester, MN

  10. A Study To Investigate The Long-Term Safety Of ZX008 (Fenfluramine Hydrochloride) Oral Solution In Children And Adults With Epileptic Encephalopathy Including Dravet Syndrome And Lennox-Gastaut Syndrome

    Rochester, MN

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