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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1481-1490 of 2762 for

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  1. Use of Peppermint Oil During Screening Colonoscopy to Improve Visibility

    Scottsdale/Phoenix, AZ

  2. A Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Subjects With Recurrent GBM

    Rochester, MN

  3. PEA for the Relief of Chemotherapy-Induced Peripheral Neuropathy

    Eau Claire, WI, Rochester, MN

  4. A Study of Nivolumab and Multi-fraction Stereotactic Radiosurgery with or without Ipilimumab in Treating Participants with Recurrent Grade II-III Meningioma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. (Apex) CGT9486 in Patients With Advanced Systemic Mastocytosis

    Scottsdale/Phoenix, AZ

  6. NKX101, Intravenous Allogeneic CAR NK Cells, in Adults With AML or MDS

    Jacksonville, FL

  7. Ascorbic Acid and Combination Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma or CCUS

    Rochester, MN, La Crosse, WI, Eau Claire, WI, Mankato, MN

  8. Ipilimumab With or Without Talimogene Laherparepvec in Unresected Melanoma

  9. Evaluation of Safety and Efficacy of Allo GDA-201 NK Cells in Patients With Relapsed/Refractory B Cell NHL

    Jacksonville, FL

  10. Dose Escalation Study of mRNA 2416 for Intratumoral Injection to Patients With Advanced Malignancies

    Scottsdale/Phoenix, AZ

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