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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1141-1150 of 7960

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  • Locations: Rochester, MN
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  1. Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury

    Rochester, MN

  2. ESWL vs. Pancreatoscopy-guided Lithotripsy for Painful Chronic Calcific Pancreatitis

    Rochester, MN

  3. Trial of Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis Associated Diabetes Mellitus

    Rochester, MN

  4. A Study to Compare Surveillance vs. Endoscopic Therapy for Barrett's Esophagus with Low-grade Dysplasia

    Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL

  5. IS-002 in Prostate Cancer

    Rochester, MN

  6. Novel Precision Medicine Approach For Obesity Trial

    Jacksonville, FL, Rochester, MN

  7. Testing the Addition of a New Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Rituximab) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

    Jacksonville, FL, Rochester, MN

  8. Testing Low Dose Tamoxifen For Invasive Breast Cancer, The (LoTam) Trial

    Albert Lea, MN, Scottsdale/Phoenix, AZ, Eau Claire, WI, Jacksonville, FL, La Crosse, WI, Mankato, MN, Rochester, MN

  9. A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

    Rochester, MN

  10. Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers (18F-FAPI-74 GI)

    Rochester, MN

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