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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study to Gain Clinical Validation of an Automated Retinal Image Analysis System (EyeQuant) with Vascular Biomarkers to Indicate Cognitive Decline

    Scottsdale/Phoenix, AZ

  2. A Study to Evaluate Feasibility of Microburst Vagus Nerve Stimulator (VNS) Therapy

    Jacksonville, FL

  3. A Study to Evaluate the Safety and Effectiveness of Metformin and Nelfinavir with Bortezomib in Patients with Relapsed and/or Refractory Multiple Myeloma

    Jacksonville, FL, Rochester, MN

  4. A Study to Evaluate the Safety and Effectiveness of Allogeneic Mesenchymal Precursor Cells for the Treatment of Heart Failure

    Rochester, MN

  5. Study to Evaluate the Efficacy and Safety of MEDI9929 (AMG 157) in Adult Subjects With Inadequately Controlled, Severe Asthma

    Rochester, MN

  6. Community Intervention to Reduce Tobacco Use in Pregnant Women

    Rochester, MN

  7. A Study to Evaluate the Accuracy of the Length-109 Probe Set Panel (a Genetic Test) in Predicting Response to Golimumab in Participants with Moderately to Severely Active Ulcerative Colitis

    Rochester, MN

  8. Occipital Nerve Stimulation (ONS) for Migraine: OPTIMISE

    Scottsdale/Phoenix, AZ

  9. Muscle Protein Metabolism in Obesity

    Scottsdale/Phoenix, AZ

  10. Effectiveness of Deep Brain Stimulation for Treating People with Treatment Resistant Obsessive-Compulsive Disorder

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