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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 3421-3430 of 11316

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  1. A Study of Arikayce for Treatment of Mycobacteria that is not Tuberculosis

    Rochester, MN

  2. To Assess Efficacy and Safety of Batoclimab in Adult Participants With Active Chronic Inflammatory Demyelinating Polyneuropathy

    Jacksonville, FL

  3. PeriCut Catheter System Early Feasibility Study

    Rochester, MN

  4. Assessing the Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes

    Jacksonville, FL, Rochester, MN

  5. Post COVID Syndrome Treatment With Variable Pulse Transcranial Magnetic Stimulation

    Rochester, MN

  6. Weight Loss Through Mayo Clinic Diet

    Rochester, MN

  7. Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough (CALM-2)

    Jacksonville, FL

  9. Effectiveness and Safety of Restylane Contour in the Treatment of Temple Hollowing

  10. A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung Cancer

    Rochester, MN

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