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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1481-1490 of 10669

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  1. Intraoperative Non-invasive Eye Movement Monitoring

    Rochester, MN

  2. Effect of Fasting, Endogenous GLP-1 Secretion on B-cell Response to Intravenous Glucose

    Rochester, MN

  3. A Study of Clinical Outcomes Data and Imaging for Patients Receiving Cartiform for Articular Cartilage Defects as Treatment

    Rochester, MN

  4. A Study to Evaluate the Safety and Tolerability of LCZ696 Followed by a 52-week Study of LCZ696 Compared With Enalapril in Pediatric Patients with Heart Failure

    Rochester, MN

  5. A Study to Understand Why Laying Down May Influence High Blood Pressure in Patient's with a Disease that Causes Problems with the Autonomic Nervous System

    Rochester, MN

  6. A Study to Gather Information About the Usability of Self-help Instructional Videos for Childhood Anxiety Disorders and Obsessive Compulsive Disorder

    Rochester, MN

  7. Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Study

    Jacksonville, FL, Rochester, MN

  8. Study of [68Ga]FAPI-46 PET in Patients With Pancreatic Ductal Carcinoma

    Rochester, MN

  9. Safety of Regional Citrate Anticoagulation Delivered by the Multifiltratepro System in Continuous Renal Replacement Therapy

    Rochester, MN

  10. COVFIS-HOME: COVID-19 Pilot Study of Fisetin to Alleviate Dysfunction and Decrease Complications

    Rochester, MN

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