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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1281-1290 of 10621

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  1. Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

    Eau Claire, WI, Mankato, MN, Rochester, MN, Jacksonville, FL

  2. Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast

  3. Hydrodissection as a Treatment for Carpal Tunnel Syndrome

    Rochester, MN

  4. Randomized Study to Assess the Safety, Pharmacokinetics/Dynamics of DS-1040b in Subjects With Acute Submassive Pulmonary Embolism

    Rochester, MN

  5. Ginseng as an Intervention to Decrease Cancer-Related Fatigue in Post-Treatment Cancer Survivors

    Scottsdale/Phoenix, AZ

  6. A Study of LY2951742 (Galcanezumab) in Participants With Cluster Headache

    Scottsdale/Phoenix, AZ

  7. The OLYMPUS Study - Optimized DeLivery of Mitomycin for Primary UTUC Study

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  8. Shared Decision Making to Improve Goals of Care Discussions in the Emergency Department

    Rochester, MN

  9. Vemurafenib and Cobimetinib in Treating Patients With BRAF V600E Mutation Positive Craniopharyngioma

    Rochester, MN, Jacksonville, FL

  10. Phase II Study of NGC-Triple Regimen in Potentially Resectable Pancreatic Cancer Patients

    Scottsdale/Phoenix, AZ, Rochester, MN

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