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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study to Compare the Outcome of Primary Anatomic Shoulder Arthroplasty Using the Stryker ReUnion System with Implantation of Either a Peg or Keel Glenoid Construction.

    Rochester, MN

  2. Mayo Clinic Pilot Studies towards Optimizing Quality of Life and Outcomes in VAD Patients

    Rochester, MN

  3. Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma (HIMALAYA)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. A Clinical Trial to Assess the Safety of a Novel Scaffold Biomaterial

    Rochester, MN

  5. Study of Intravenous Sodium Thiosulfate in Acute Calciphylaxis Patients

  6. A Study to Evaluate the Safety and Effectiveness of BMS-986036 (pegbelfermin) in Adults with Nonalcoholic Steatophepatitis (NASH) and Compensated Liver Fibrosis

    Jacksonville, FL

  7. A Study to Evaluate the Safety, Tolerability, and Clinical Benefit of AK002 in Adult Patients with Mast Cell Gastritis and/or Gastroenteritis

    Rochester, MN

  8. Adult Spinal Deformity Surgery Real-World Functional Activity

    Rochester, MN

  9. Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies

    Scottsdale/Phoenix, AZ

  10. Ketamine Infusions in Clinically Depressed ICU Patients

    Jacksonville, FL

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