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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Positron Emission Tomography Using 64Cu-SAR-bisPSMA In Participants With High-risk Prostate Cancer Prior To Radical Prostatectomy

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. A Study Of IDRX-42 (GSK6042981) Versus (vs) Sunitinib In Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Study To Assess Adverse Events And Effectiveness Of IntraVenous Infusions Of ABBV-CLS-628 In Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

    Jacksonville, FL, Rochester, MN

  4. Aliya™ Pulsed Electric Fields (PEF) Delivered Prior To Standard Of Care Treatment For Advanced Cancer

    Jacksonville, FL, Rochester, MN

  5. Testing The Addition Of High Dose, Targeted Radiation To The Usual Treatment For Locally-Advanced Inoperable Non-small Cell Lung Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. Venetoclax In Combination With ASTX727 For The Treatment Of Chronic Myelomonocytic Leukemia And Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  7. A Phase 3 Randomized, Placebo-controlled, Double-blind Study Of Niraparib In Combination With Abiraterone Acetate And Prednisone Versus Abiraterone Acetate And Prednisone For Treatment Of Subjects With Metastatic Prostate Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  8. A Study To Evaluate The Safety, Effectiveness And Tolerability Of APG-2575 In Patients With Waldenström Macroglobulinemia

    Jacksonville, FL

  9. Study To Improve Health-related Quality Of Life (HRQOL) In Black Prostate Cancer Patients (CaPQoL) Through Whole Person Survivorship Care

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  10. Empty Bladder Impact During Radiation Therapy For Prostate Cancer

    Albert Lea, MN, Scottsdale/Phoenix, AZ, Eau Claire, WI, Jacksonville, FL, La Crosse, WI, Mankato, MN, Rochester, MN

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