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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Dermatome Electrical Stimulation on Individuals With Overweight and Class I Obesity

    Rochester, MN

  2. A Study of Cediranib and Olaparib Combined, Compared to Either Drug Alone, or to a Standard Chemotherapy in Treating Patients who have a Return of Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

    La Crosse, WI, Rochester, MN, Mankato, MN

  3. Supporting Patients Undergoing HIgh-Risk PCI Using a High-Flow PErcutaneous Left Ventricular Support Device

    Rochester, MN

  4. A Study of Pre-Surgery Inspiratory Muscle Training for Patients who will have Surgery on Their Esophagus

    Rochester, MN

  5. MARK 1A Series: Percutaneous Microwave Ablation for Patients With Lung Tumor(s)

  6. A Study of the Safety, Tolerability and Effectiveness of Eleclazine on Shortening the QT Interval in Adults with Long QT-3 Syndrome

    Rochester, MN

  7. A Study of Donated Alloantigen Reactive Regulatory T Cells for Reducing or Discontinuing Immune System Suppression in Liver Transplant Patients

    Rochester, MN

  8. Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC).

    Scottsdale/Phoenix, AZ

  9. A Phase I/II, open-label, multi-center trial of [177Lu]Lu-NeoB in combination with capecitabine in adult patients with GRPR+, ER+, HER2- metastatic breast cancer after progression on previous endocrine therapy in combination with a CDK4/6 inhibito

    Rochester, MN

  10. An Investigational Immuno-therapy Study to Assess the Safety, Tolerability and Effectiveness of Anti-LAG-3 With and Without Anti-PD-1 in the Treatment of Solid Tumors

    Rochester, MN

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