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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study to Investigate the Performance of Dual Energy CT for the Detection of Breast Implant Rupture and Extra-capsular Silicone Compared to Standard MRI Exams.

  2. SURPASS: A Randomized, Double-Blind, Multicenter Study of the Efficacy, Safety, and Tolerability of Brincidofovir Versus Valganciclovir for the Prevention of Cytomegalovirus (CMV) Disease in CMV Seropositive Kidney Transplant Recipients

    Rochester, MN

  3. A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Co-Administration of ABT-493 and ABT-530 With and Without RBV in Subjects With Chronic Hepatitis C Virus (HCV) Genotypes 2, 3, 4, 5 or 6 Infection

    Scottsdale/Phoenix, AZ

  4. A Study of the Safety and Effectiveness of Blenderized Tube Feedings in Adult Patients on Home Enteral Nutrition

    Rochester, MN

  5. Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

    Rochester, MN

  6. An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the Cancer

    Rochester, MN

  7. A Study of the Effect of Treatment on Activity and Muscle Function in Pediatric Patients with Scoliosis

    Rochester, MN

  8. A Study of Facial Nerve Monitoring During Surgical Removal of the Parotid Gland for Superficial Benign Lesions

    Rochester, MN

  9. A Study to Understand the Perceptions of Patients, Family Members and Caregivers About Their Role for Engagement in Research

    Rochester, MN

  10. A Study Using Prothrombin Complex Concentrate versus Fresh Frozen Plasma for Post Cardiopulmonary Bypass Surgery Clotting Problems and Bleeding

    Rochester, MN

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