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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 5961-5970 of 11700

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  1. The Relationship between Star Excursion Balance Test Performance and Hip Strength, Self- Report Outcomes and Core Stability in Patients 12 Weeks Status Post Hip Arthroscopy

    Minneapolis, MN

  2. Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma

  3. A Study of the Effects of Pregabalin on Colon Function

    Rochester, MN

  4. Decision Aid for Shared Decision Making in Acute Respiratory Failure

    Rochester, MN

  5. Shared Decision Making in Patients with Neck and Back Pain – Options in Neck and Back Pain Management

    Rochester, MN

  6. Weight Gain and Adipose Tissue

    Rochester, MN

  7. A Study to Evaluate Reducing Stroke by Screening for Undiagnosed Atrial Fibrillation in Elderly Individuals

    Eau Claire, WI, Rochester, MN, La Crosse, WI

  8. A Study to Evaluate Base-in Prism Spectacles for Intermittent Exotropia

    Rochester, MN

  9. Imaging in Wrist Musculoskeletal MRI

    Rochester, MN

  10. Does Early Administration of Tranexamic Acid Reduce Blood Loss and Perioperative Transfusion Requirement

    Rochester, MN

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