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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Nanopore Sequencing for Detecting Bacteria in Bile and Preventing Surgical Site Infections in Patients Undergoing Surgery for Benign or Malignant Pancreatic Tumors

    Rochester, MN

  2. Rem-422, an MYB mRNA Degrader, in Patients With Relapsed/Refractory AML or Higher-Risk MDS

    Jacksonville, FL

  3. A Study of the Use of Preoperative Antibiotics Given Preventively Prior to Kidney Stone Surgery to Patients at Moderate Risk of Infection

    Scottsdale/Phoenix, AZ

  4. A Study to Evaluate the Effectiveness, Safety and Movement of Ustekinumab in Pediatric Patients with Ulcerative Colitis

    Rochester, MN

  5. Family Centered Wellness Coaching Program in Patients at High Risk for Developing Diabetes

    Rochester, MN

  6. A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Subjects With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Study to Evaluate Outcomes of Proximal Hamate to Scaphoid Transfer in the Setting of Unsalvageable Proximal Pole Scaphoid Nonunions

    Rochester, MN

  8. Will Making the HPV Vaccine Available at Mayo Clinic Express Care with Use of Electronic Point of Care Reminder Improve Overall Vaccination Rates Among an Empaneled Adolescent Population?

    Rochester, MN

  9. A Study to Evaluate the Safety and Effectiveness of the Multi-Electrode Radiofrequency Balloon Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation

  10. A Study to Evaluate Prevention of Paclitaxel-Associated Neuropathy with Fingolimod

    Rochester, MN

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