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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.

    Jacksonville, FL

  2. Behavioral Interventions to Prevent or Delay Dementia

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. Study to Evaluate Efficacy and Safety of Two Drug Regimens in Subjects with Moderate to Severe Crohn's Disease

    Rochester, MN

  4. Study to Treat Symptoms of Ibs With Diarrhea Using Combination Therapy of a Low-Fodmap Diet and a Neuromodulator

    Jacksonville, FL

  5. Improving Outcomes in PICS with Home-Based Program of Rehabilitation and Health Coaching

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. A Study of Oral Kavalactones Effect on Nurses

    Rochester, MN

  7. Ivosidenib, Nivolumab, and Ipilimumab Combination in Previously Treated Subjects with Nonresectable or Metastatic IDH1-Mutant Cholangiocarcinoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. Subjective Sleep Quality of Patients With Chronic Insomnia

    Jacksonville, FL

  9. Behavioral Health Techniques with Fibromyalgia

    Rochester, MN

  10. A Study of Macitentan in Pulmonary Hypertension After Left Ventricular Assist Device Implantation

    Scottsdale/Phoenix, AZ

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