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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 281-290 of 578 for sleep

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  1. VX15/2503 in Combination With Avelumab in Advanced Non-small Cell Lung Cancer

    Jacksonville, FL, Rochester, MN

  2. A Study of a Psychotherapeutic Approach Applied to Those Who are Critically Ill to Provide Patients with Psychological Support

    Rochester, MN

  3. A Study to Compare High Versus Low Bicarbonate Bath in Critically-ill Patients Receiving Continuous Renal Replacement Therapy

    Rochester, MN

  4. Study of Nivolumab Combined With Ipilimumab Versus Pemetrexed and Cisplatin or Carboplatin as First Line Therapy in Unresectable Pleural Mesothelioma Patients

    Rochester, MN

  5. A Study to Evaluate Whether or Not Selexipag is Effective and Safe in Patients with Chronic Thromboembolic Pulmonary Hypertension when the Disease is Inoperable or Persistent/Recurrent After Surgery

    Jacksonville, FL

  6. Safety Study of Inhaled Saline in Acute Lung Injury

    Rochester, MN

  7. Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE

    Jacksonville, FL, Rochester, MN

  8. Low Dose Computed Tomography for Lung Cancer Screening

  9. Immune Response to Pneumococcal Polysaccharide Vaccine (23-valent) Predicts Asthma Status and Outcomes in Late Adolescents With Asthma

    Rochester, MN

  10. A Study of Pulmonary Rehabilitation in Patients with Idiopathic Pulmonary Fibrosis (IPF)

    Rochester, MN

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