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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 131 for melanoma

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  1. A Study to See if New Device Technology Can Tell the Difference Between Non-cancer and Cancerous Melanoma

    Scottsdale/Phoenix, AZ

  2. A Study Comparing Temozolomide and Selumetinib for Treating Patients with Metastatic Melanoma of the Eye

    Rochester, MN

  3. Dasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By Surgery

    Rochester, MN

  4. Melanoma Relatlimab Nivolumab

    Jacksonville, FL, Rochester, MN

  5. Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Melanoma of the Eye

    Rochester, MN

  6. Minimally Invasive Groin Dissection for Melanoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Study of the Effectiveness of Stress Management Therapy for Patients with Melanoma

    Rochester, MN

  8. Neoadjuvant Combination Targeted and Immunotherapy for Patients With High-Risk Stage III Melanoma

    Rochester, MN, Jacksonville, FL

  9. Study of a Melanoma Vaccine in Stage IIb, IIc, and III Melanoma Patients

    Rochester, MN

  10. Neoadjuvant Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Cutaneous Stage L-lll Melanoma

    Rochester, MN

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