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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 42 for inflammatory bowel disease

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  • Study status: Open/Status Unknown
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  1. Validation of Pediatric Inflammatory Bowel Disease Knowledge Questions (Emma)

    Rochester, MN

  2. A Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Intravenous (IV) Infusion and Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Crohn's Disease

    Rochester, MN

  3. A Study to Evaluate the Effectiveness and Safety of Apraglutide in Adults with Short Bowel Syndrome and Intestinal Failure

    Rochester, MN

  4. A Study to Evaluate the Effectiveness, Safety and Movement of Ustekinumab in Pediatric Patients with Moderate-to-Severe, Active Crohn's Disease

    Rochester, MN

  5. Study Comparing Intravenous (IV)/Subcutaneous (SC) Risankizumab to IV/SC Ustekinumab to Assess Change in Crohn's Disease Activity Index (CDAI) in Adult Participants With Moderate to Severe Crohn's Disease (CD)

    Rochester, MN

  6. A Study to Evaluate Posaconazole to Treat Genetically-defined Patients with Active Crohn's Disease

    Rochester, MN

  7. A Study to Evaluate the Effectiveness, Safety and Movement of Ustekinumab in Pediatric Patients with Ulcerative Colitis

    Rochester, MN

  8. A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Ulcerative Colitis

    Rochester, MN

  9. The Influence of Diet on Gut Microbiotas

    Rochester, MN

  10. An Investigational Study of Experimental Medication BMS-986165 in Participants With Moderate to Severe Crohn's Disease

    Jacksonville, FL

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