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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 212 for infectious diseases

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  1. A Study to Evaluate Biomarkers of Fluoroquinolone-induced Mitochondrial Toxicity

    Rochester, MN

  2. Expanded Access Use of Brincidofovir for BK Polyomavirus

    Rochester, MN

  3. Study to Evaluate the Safety, Pharmacokinetics and Clinical Benefit of FLU-IGIV in Hospitalized Patients with Serious Influenza A Infection

    Rochester, MN

  4. SER-109 Versus Placebo to Prevent Recurrent Clostridium Difficile Infection (RCDI)

    Rochester, MN

  5. Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD3)

    Scottsdale/Phoenix, AZ

  6. A Study Using VE303 to Prevent Recurrence of Clostridium Difficile Infection

    Rochester, MN

  7. Fecal Microbiota Transplantation for C. Difficile Infection in Solid Organ Transplant Recipients

    Rochester, MN

  8. A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of ABBV-181 (Budigalimab) in Adult Participants With HIV-1

    Rochester, MN

  9. Study Using Clofazimine to Treat Patients with Non-Tuberculous Mycobacterial Infections

    Scottsdale/Phoenix, AZ

  10. Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection

    Scottsdale/Phoenix, AZ

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