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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 11 for hpv

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  • Study status: Open/Status Unknown
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  1. A Study to Enhance Provider Recommendations for HPV Vaccination

    Rochester, MN

  2. A Study to Evaluate Acceptance and Completion Rate of Free HPV Vaccination Among Uninsured Low Income Adult Patients

    Jacksonville, FL

  3. A Study to Evaluate Mucosal Sparing Adjuvant Radiotherapy After Surgical Exploration In HPV Head And Neck Cancer

    Rochester, MN, Scottsdale/Phoenix, AZ

  4. A Study to Evaluate PDS0101 and Pembrolizumab Combination to Treat Subjects with HPV16 + Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

    Rochester, MN, Jacksonville, FL, Scottsdale/Phoenix, AZ

  5. A Study to Validate HPV DNA Genotyping and Prognostic Genomic Biomarkers for Diagnosis

    Rochester, MN

  6. A Study to Evaluate Human Papilloma Virus Circulating Tumor DNA in Cervical Cancer

    Rochester, MN

  7. A Study of Genital Cytology and Pathology in Patients with Confirmed HPV Associated Oropharyngeal Carcinoma

    Rochester, MN

  8. Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers

    Jacksonville, FL, Rochester, MN

  9. A Study to Evaluate Mutanome-directed Immunotherapy in Patients with Squamous Cell Carcinoma of the Head and Neck

    Jacksonville, FL

  10. Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer and Cervical Cancer: a Phase II Clinical Study

    Rochester, MN

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