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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 621-630 of 969 for hematology

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  1. International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)

    Rochester, MN

  2. Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MF

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  3. Study of LY2784544 Testing Alternative Dosing in Participants with Myeloproliferative Neoplasms

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  4. The Role of Highly Selective Androgen Receptor (AR) Targeted Therapy in Men With Biochemically Relapsed Hormone Sensitive Prostate Cancer

  5. S1011 Standard or Extended Pelvic Lymphadenectomy in Treating Patients Undergoing Surgery for Invasive Bladder Cancer

    Rochester, MN

  6. Evaluation of t-RFA and RF-TVA Prior to/Following Radiation Therapy to Treat Painful Metastatic Vertebral Body Tumor(s)

    Rochester, MN

  7. Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapy

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. A Dose Escalation and Expansion Study of ASP4132 to Subjects With Advanced Refractory Tumors and Lymphoma

    Rochester, MN, Scottsdale/Phoenix, AZ

  9. A Study to Evaluate Pevonedistat, Azacitidine (or Decitabine), and Venetoclax (PAVE) to Treat Acute Myelogenous Leukemia (AML) Patients

    Rochester, MN

  10. ACP-196 in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

    Rochester, MN, Jacksonville, FL

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