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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 61-70 of 304 for heart disease

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  1. A Study to Understand the Perceptions of Patients, Family Members and Caregivers About Their Role for Engagement in Research

    Rochester, MN

  2. A Study of the Effect of Dapagliflozin on Symptoms and Biomarkers in Diabetes Patients with Heart Failure

    Rochester, MN

  3. A Study to Evaluate the Utility of Focused Frailty Interventions on Patients with Advanced Heart Failure

    Rochester, MN

  4. Cardiovascular Effects of Energy Drinks in Healthy Adults

    Rochester, MN

  5. The Ventilatory Response to Activation of the Locomotor Afferents in Normoxic and Hypoxic Conditions

    Rochester, MN

  6. International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)

  7. Trifecta™ GT Post Market Clinical Follow-up

    Rochester, MN

  8. Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects With Elevated Risk

    Scottsdale/Phoenix, AZ

  9. Virtual World-based Cardiac Rehabilitation Program to Encourage Healthy Lifestyle Choices Among Cardiac Patients

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. A Study to Evaluate the Effect of the Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Blocker, GSK2798745, on Pulmonary Gas Transfer and Respiration in Patients With Congestive Heart Failure

    Rochester, MN

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