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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-16 of 16 for endocrine AND surgery

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  1. Alisertib and Fulvestrant in Treating Patients With Hormone Receptor Positive Breast Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

    Rochester, MN

  2. A Study to Understand Sex-Specific Effects of Endocrine Disruption on Physical Activity

    Rochester, MN

  3. A Study to Evaluate Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

    Rochester, MN

  4. A Study to Predict Recovery from Cushing Syndrome

    Rochester, MN

  5. Biomarker Expression in Patients With ACTH-Dependent Cushing's Syndrome Before and After Surgery

    Rochester, MN

  6. Lobular Involution-Based Response to Antiendocrine Therapy for Women with Breast Atypical Hyperplasia

    Jacksonville, FL

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