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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 27 for emergency

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  1. Shared Decision Making to Improve Goals of Care Discussions in the Emergency Department

    Rochester, MN

  2. A Study to Evaluate the Performance of a Patient Self-reported, Digital Admission Reporting Software for the Emergency Department

    Rochester, MN

  3. A Study to Evaluate Shared Decision Making for Patients with Minor Head Injury

    Rochester, MN

  4. A Study to Evaluate Patiromer for the Management of Hyperkalemia in Subjects Receiving Renin-Angiotensin Aldosterone System Inhibitor (RAASi) Medications for the Treatment of Heart Failure (DIAMOND)

    Jacksonville, FL

  5. A Study to Evaluate Agents to Treat Moderately or Severely Ill Patients with Severe Acute Respiratory Syndrome Coronavirus 2

    Rochester, MN

  6. A Study to Assess Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia

    Rochester, MN, Mankato, MN

  7. A Study to Evaluate Physical Therapy in the Emergency Department

    Rochester, MN

  8. Colorectal Resection in Emergency General Surgery

    Rochester, MN

  9. A Study to Evaluate Chest Pain Risk Stratification Using HEART Pathway in Community Emergency Departments

    Eau Claire, WI

  10. A Study to Evaluate SOLIRIS® to Treat Participants with Coronavirus Disease 2019

    Rochester, MN

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