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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 12 for covid-19

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Effectiveness of Merimepodib in Adult Patients with Advanced COVID-1

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  2. Losartan for Outpatients on COVID-19

    Rochester, MN

  3. A Study to Generate Algorithms for Early Prediction of Aggressive Progression and Hospitalization in Patients Diagnosed with SARS-CoV-2/COVID-19 Infection

    Rochester, MN

  4. A Study to Evaluate the Efficacy and Safety of Colchicine on Coronavirus SARS-CoV2 Positive Adults

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  5. Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine

    Rochester, MN

  6. A Study to Assess Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia

    Rochester, MN

  7. Development of Potential COVID-19 Vaccine and Serological Assay

    Rochester, MN

  8. A Study to Evaluate COVID19 Pregnancy Risks

    Rochester, MN

  9. COVID-19 Remote Monitoring

    Jacksonville, FL

  10. Tele-Medicine in an Advanced Prostate Cancer Clinic

    Rochester, MN

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