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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 38 for covid-19

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Positive SARS-CoV-2 Antibodies in Subjects with Bipolar Disorder

    Rochester, MN

  2. A Study to Evaluate Convalescent Plasma to Stem Coronavirus

    Scottsdale/Phoenix, AZ

  3. Research to Test Whether Doing Exercise Training Helps Lessen or Prevent the Longer-term Symptoms of COVID-19 Infection

    Jacksonville, FL

  4. A Study to Evaluate Filter Comparison for Reducing COVID-19 Infection Risk

    Rochester, MN

  5. A Study to Evaluate the Safety and Effectiveness of Antithrombotics to Treat Hospitalized COVID-19 Patients

    Scottsdale/Phoenix, AZ

  6. Recovery of Respiratory System in COVID-19 Patients

    Scottsdale/Phoenix, AZ, Rochester, MN

  7. Study to Evaluate the Effectiveness and Safety of Remdesivir in Participants with Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019

    Jacksonville, FL, Rochester, MN

  8. Health Coaching Post COVID

    Rochester, MN

  9. Acupuncture Therapy for COVID-Related Olfactory Loss

    Rochester, MN

  10. A Study to Evaluate Agents to Treat Moderately or Severely Ill Patients with Severe Acute Respiratory Syndrome Coronavirus 2

    Rochester, MN

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