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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 31 for covid-19

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Positive SARS-CoV-2 Antibodies in Subjects with Bipolar Disorder

    Rochester, MN

  2. Research to Test Whether Doing Exercise Training Helps Lessen or Prevent the Longer-term Symptoms of COVID-19 Infection

    Jacksonville, FL

  3. A Study to Analyze Potential Long-term Treatments for Covid-19 Recovery

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. Recovery of Respiratory System in COVID-19 Patients

    Scottsdale/Phoenix, AZ, Rochester, MN

  5. Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

    Rochester, MN

  6. Health Coaching Post COVID

    Rochester, MN

  7. Acupuncture Therapy for COVID-Related Olfactory Loss

    Rochester, MN

  8. Mindfulness Intervention for Post-Covid Symptoms

    Rochester, MN

  9. A Study to Evaluate the Effectiveness and Safety of Remdesivir to Treat Coronavirus Disease 2019 in an Outpatient Setting

    Rochester, MN

  10. A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People with Weakened Immune Systems or at Increased Risk for Poor Outcomes who are Hospitalized Due To Severe COVID-19

    Jacksonville, FL

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