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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 44 for covid-19

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  • Study status: Open/Status Unknown
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  1. A Study to Compare Saliva and Swab Specimens in Detection of COVID Severe Acute Respiratory Syndrome

    Albert Lea, MN, Austin, MN, Red Wing, MN, Owatonna, MN, Rochester, MN, Mankato, MN

  2. A Study to Evaluate Positive SARS-CoV-2 Antibodies in Subjects with Bipolar Disorder

    Rochester, MN

  3. A Study to Evaluate Convalescent Plasma to Stem Coronavirus

    Scottsdale/Phoenix, AZ

  4. A Study to Evaluate Treatment for Outpatients with COVID-19

    Jacksonville, FL

  5. Research to Test Whether Doing Exercise Training Helps Lessen or Prevent the Longer-term Symptoms of COVID-19 Infection

    Jacksonville, FL

  6. Continuous Glucose Monitor (CGM) Use in COVID-19 Patients

    Jacksonville, FL

  7. Study to Evaluate the Effectiveness and Safety of Remdesivir in Participants with Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019

    Jacksonville, FL, Rochester, MN

  8. A Study to Evaluate Agents to Treat Moderately or Severely Ill Patients with Severe Acute Respiratory Syndrome Coronavirus 2

    Rochester, MN

  9. A Study to Evaluate SOLIRIS® to Treat Participants with Coronavirus Disease 2019

    Rochester, MN

  10. A Study to Evaluate Rivaroxaban to Reduce Risk of Major Venous and Arterial Thrombotic Events, Hospitalization and Death in Medically Ill Outpatients with Acute COVID-19 Infection

    Rochester, MN

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