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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 381-390 of 833 for cardiovascular

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  1. Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

    Rochester, MN

  2. A Study Using Magnetic Resonance Elastography to Assess Heart Muscle Stiffness in Patients with Cardiac Amyloidosis

    Rochester, MN

  3. Efficacy and Safety of Intranasal MSP-2017 for the Conversion of PSVT to Sinus Rhythm (NODE-1)

    Scottsdale/Phoenix, AZ

  4. Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  5. A Study to Evaluate the Safety and Effectiveness of GORE® CARDIOFORM Septal Occluder to Treat Migraine Headaches

    Scottsdale/Phoenix, AZ

  6. Investigational Device Evaluation of the WATCHMAN FLX™ LAA Closure Technology

  7. Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim 3)

    Rochester, MN

  8. Evaluation of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms

    Rochester, MN

  9. Oral Treprostinil in Subjects With Pulmonary Hypertension (PH) Associated With Heart Failure With Preserved Ejection Fraction (HFpEF)

    Jacksonville, FL

  10. A Study to Evaluate Intracoronary CD34+ Cell Administration in Patients With Early Coronary Atherosclerosis

    Rochester, MN

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