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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-8 of 8 for cardiac amyloidosis

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  • Study status: Open/Status Unknown
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  1. Imaging of Systemic Light Chain Cardiac Amyloidosis and Whole-Body Amyloidosis

    Jacksonville, FL

  2. A Study to Monitor Cardiac Amyloidosis Patients with Implantable Event Monitors

    Rochester, MN

  3. Expanded Access Protocol of Patisiran for Patients With Hereditary ATTR Amyloidosis (hATTR)

    Rochester, MN

  4. A Study to Evaluate the Safety and Effectiveness of CAEL-101 and Plasma Cell Dyscrasia Treatment vs. Placebo and Plasma Cell Dyscrasia Tretment to Treat Patients with Mayo Stage IIIb AL Amyloidosis

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. Intracardiac Flow Assessment in Cardiac Amyloidosis

    Rochester, MN

  6. A Study to Collect Data and Blood Samples from Mayo Patients Who Have or are Suspected of Having Amyloidosis, or Their Family Members, for Future Research

    Rochester, MN

  7. Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic Stenosis

    Rochester, MN

  8. Blood-based Biomarkers for Early Disease Detection in Cardiac Amyloidosis

    Scottsdale/Phoenix, AZ


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