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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 641-650 of 1772 for cancer

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  1. Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma

  2. MR-Guided Laser Ablation of Hepatic Tumors

    Rochester, MN

  3. Radiation Therapy With Or Without Cetuximab In Treating Patients Who Have Undergone Surgery For Locally Advanced Head And Neck Cancer

    Albert Lea, MN, Jacksonville, FL, La Crosse, WI, Mankato, MN, Rochester, MN

  4. (Apex) Bezuclastinib In Patients With Advanced Systemic Mastocytosis

    Scottsdale/Phoenix, AZ

  5. Rituximab, Pentostatin, Cyclophosphamide, and Lenalidomide in Treating Patients With Previously Untreated B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. Study Of RYZ401 In Subjects With Solid Tumors Expressing SSTRs.

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Enhancing Facial Nerve Neuroprotection and Regeneration Through Omega-3 Supplementation Following Vestibular Schwannoma Resection

    Rochester, MN

  8. Phase 2 Study Of Inhaled Lipid Cisplatin In Pulmonary Recurrent Osteosarcoma

    Rochester, MN

  9. Study To Compare Contrast-Enhanced Ultrasound, Contrast-Enhanced Dual Energy Mammography, And Contrast-Enhanced Breast MR For Early Breast Cancer Detection

    Rochester, MN

  10. Dasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By Surgery

    Rochester, MN

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