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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 693 for cancer

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  1. A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

    Jacksonville, FL, Rochester, MN

  2. A Study of PF-08052666/​SGN-MesoC2 in Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. NL-201 in Patients With Relapsed or Refractory Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. Dual BET and CBP/p300 Inhibitor in Patients With Targeted Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors (SPX-303)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Study of RP-6306 Alone or in Combination With RP-3500 in Patients With Advanced Solid Tumors

    Jacksonville, FL, Rochester, MN

  8. A Comparison of TULSA Procedure vs. Radical Prostatectomy in Participants With Localized Prostate Cancer (CAPTAIN)

    Rochester, MN, Jacksonville, FL

  9. Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

    Jacksonville, FL, Rochester, MN

  10. A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN

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