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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 693 for cancer

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  • Study status: Open/Status Unknown
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  1. Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)

    Scottsdale/Phoenix, AZ, Rochester, MN

  2. SRG-514 Administered Intraoperatively to Patients Undergoing Breast-conserving Cancer Surgery

    Rochester, MN

  3. Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

    Jacksonville, FL

  4. Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. A First-in-human Study of 3HP-2827 in Patients With Unresectable or Metastatic Solid Tumors With FGFR2 Alterations

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A First-in-Human Study of BG-C137, an Anti-FGFR2b Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

    Rochester, MN

  8. Study to Improve health-related quality of life (HRQOL) in Black Prostate Cancer Patients (CaPQoL) through Whole Person Survivorship Care

    Jacksonville, FL

  9. A Study Evaluating the Safety and Effectiveness of Therapies in Patients with Metastatic Colorectal Cancer (INTRINSIC)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. A Study to Evaluate the Safety and Therapeutic Activity of GI-102 in Patients With Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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