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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1351-1360 of 2916 for cancer

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  1. Rituximab, Bendamustine Hydrochloride, and Lenalidomide in Treating Patients with Refractory or Relapsed Indolent Non-Hodgkin Lymphoma

    Rochester, MN

  2. A Phase 1/2 Study Of CYT-0851 In B-Cell Malignancies And Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. AKT Inhibitor MK2206, Combined with Bendamustine Hydrochloride, and Rituximab for Treating Patients who have Relapsed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

  4. OsteoCool Tumor Ablation Post-Market Study

    Rochester, MN

  5. S1304, Carfilzomib And Dexamethasone For Treating Patients With Relapsed Or Refractory Myeloma

    Jacksonville, FL, Rochester, MN

  6. Evaluation of the Effect of Fasting and Exercise on Uptake of Tc-99m Sestamibi in Breast Tissue

  7. A Phase II, Multicenter Study Of The EZH2 Inhibitor Tazemetostat In Adult Subjects With INI1-Negative Tumors Or Relapsed/Refractory Synovial Sarcoma

    Jacksonville, FL

  8. A Study Of Circulating Nucleic Acid Tumor Markers Found In Different Components Of Blood

    Rochester, MN

  9. Focal Prostate Ablation Utilizing TULSA Profound System

    Rochester, MN

  10. Highly Selective CDK7 Inhibitor Q901 In Selected Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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