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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1241-1250 of 2762 for cancer

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  1. Combination Chemotherapy in Treating Patients with Non-Metastatic Extracranial Ewing Sarcoma

    Rochester, MN

  2. A Study of Treatment with Docetaxel and Prednisone, with or without Vaccine Therapy, for Patients who have Metastatic Hormone-Resistant Prostate Cancer

    Jacksonville, FL, Rochester, MN

  3. To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis

    Scottsdale/Phoenix, AZ

  4. A Study to Evaluate EAA181 to Treat Newly-diagnosed Multiple Myeloma

    La Crosse, WI, Rochester, MN

  5. LGX818 and MEK162 in Combination With a Third Agent (BKM120, LEE011, BGJ398 or INC280) in Advanced BRAF Melanoma

  6. A Study to Evaluate Genetic Testing in Guiding Treatment for Patients with Brain Metastases

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Avelumab In Patients With Previously Treated Advanced Stage Classical Hodgkin's Lymphoma (JAVELIN HODGKINS)

    Rochester, MN

  8. Birinapant With 5-azacitidine in MDS Subjects Who Are Naïve, Have Relapsed or Are Refractory to 5-azacitidine Therapy

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  9. Adipose-Derived Mesenchymal Stem Cells (AMSCs) For Recurrent Glioblastoma

    Jacksonville, FL

  10. Study to Evaluate 99mTc-MIP-1404 SPECT/CT Imaging in Men With Biopsy Proven Low-Grade Prostate Cancer

    Rochester, MN, Rochester, MN

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