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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 141-150 of 421 for breast cancer

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  1. Team Based Psychosocial Care to Promote, Maintain and Restore Wellness of Breast Cancer Patients

  2. Trial Of 225Ac-DOTATATE (RYZ101) Alone And With Pembrolizumab In Subjects With ER+, HER2-negative Unresectable Or Metastatic Breast Cancer Expressing SSTRs (TRACY-1)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Trial Of 15 Fraction Vs 25 Fraction Pencil Beam Scanning Proton Radiotherapy After Mastectomy In Patients Requiring Regional Nodal Irradiation

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. Gene Therapy For HER-Positive Cancer (SENTRY-HER2)

    Jacksonville, FL, Rochester, MN

  5. Molecular Breast Imaging (MBI) in Patients With Suspected Ductal Carcinoma in Situ (DCIS)

    Rochester, MN

  6. Lasofoxifene And Abemaciclib To The Combination Of Fulvestrant And Abemaciclib For Locally Advanced Or Metastatic ER+/HER2− Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy Or Plus Camizestrant In HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, Or PALB2m Advanced Breast Cancer

    Jacksonville, FL, Rochester, MN

  8. Comprehensive Genetic Assessment, Risk And Education In A Mammography Pilot

    Scottsdale/Phoenix, AZ

  9. Study Of DS-8201a In Subjects With Advanced Solid Malignant Tumors

    Jacksonville, FL

  10. Study Of Sacituzumab Govitecan-hziy And Pembrolizumab Versus Treatment Of Physician's Choice And Pembrolizumab In Patients With Previously Untreated, Locally Advanced Inoperable Or Metastatic Triple-Negative Breast Cancer (ASCENT-04)

    Rochester, MN

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