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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-16 of 16 for als

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  • Study status: Open/Status Unknown
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  1. Phase 2 Study for SAR443820 in Participants With Amyotrophic Lateral Sclerosis (ALS)

    Jacksonville, FL

  2. Target ALS Biomarker Study

    Jacksonville, FL

  3. Immune Phenotyping in Amyotrophic Lateral Sclerosis

    Rochester, MN

  4. Blood and Spinal Fluid Collection for Research Studies in Motor Neuron Disease and Motor Neuropathy

    Rochester, MN

  5. A Phase 3, Open-Label Extension of Reldesemtiv

    Jacksonville, FL

  6. Radicava® (Edaravone) Biomarker Study in Participants with Amyotrophic Lateral Sclerosis

    Jacksonville, FL

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