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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 13 for alcoholic hepatitis

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  1. Trial of Anakinra (Plus Zinc), or Prednisone in Patients With Severe Alcoholic Hepatitis

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Safety and Efficacy of IMM 124-E for Patients with Severe Alcoholic Hepatitis

    Rochester, MN

  3. Use of F-652 in Patients With Alcoholic Hepatitis

    Mankato, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. A Phase 2b Study in Subjects With Alcoholic Hepatitis to Evaluate Safety and Efficacy of DUR-928 Treatment

    Scottsdale/Phoenix, AZ

  5. Study of IDN-6556 in Patients With Severe AH and Contradictions to Steroid Therapy

    Rochester, MN

  6. Trial of Obeticholic Acid in Patients with Moderately Severe Alcoholic Hepatitis (AH)

    Rochester, MN

  7. A Study to Evaluate the Safety of Acamprosate for Alcohol Use Disorder

    Mankato, MN, Rochester, MN

  8. Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics

    Rochester, MN

  9. A Study to Assess the Efficacy, Safety, and Tolerability of Oral LPCN 1148 in Male Subjects With Cirrhosis of the Liver and Sarcopenia

    Scottsdale/Phoenix, AZ

  10. A Study to Establish an Alcoholic Hepatitis Network

    Rochester, MN

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