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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 12 for acosta

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  1. Characterization of Bile Acid Pathway in Obesity

    Rochester, MN

  2. Bariatric Surgery Versus Diet Alone in the Bile Acid Pathway and Weight Loss

    Rochester, MN

  3. A Study to Evaluate Phentermine-Topiramate Extended Release Pharmacotherapy vs Placebo Among Patients Using a Wearable Activity Tracker

    Rochester, MN

  4. A Study to Evaluate Individualized Lifestyle Intervention for Obesity Management Based on Obesity Phenotypes

    Rochester, MN

  5. A Study to Evaluate Setmelanoitide to Treat Patients with Rare Genetic Disorders of Obesity

    Rochester, MN

  6. Ox Bile- Conjugated Bile Acids Sodium in Type II Diabetes Mellitus

    Rochester, MN

  7. A Study of Individualized Obesity Pharmacotherapy Based on Obesity Phenotypes

    Rochester, MN

  8. A Study to Establish an Obesity-Related Phenotype Registry

    Rochester, MN

  9. Investigating if Rapid Gastric Emptying Predicts Future Weight Gain

    Rochester, MN

  10. A Study to Evaluate Using Pulsed Arterial Spin Labeling Magnetic Resonance Imaging (PASL-MRI) to Study the Function of the Hypothalamus in Anorexia and Obesity

    Rochester, MN

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