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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 164 for Prostate cancer

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  1. A Comparison of TULSA Procedure vs. Radical Prostatectomy in Participants With Localized Prostate Cancer (CAPTAIN)

    Rochester, MN, Jacksonville, FL

  2. A Study to Assess Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients with Prostate Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. Focal Laser Ablation of Prostate Cancer Tumors

    Rochester, MN

  4. A Study of Single Patient Investigational Drug CPI-613 for Use in Treatment-Refractory, Metastatic Prostate Cancer

    Rochester, MN

  5. A Study of Abiraterone Acetate Plus Prednisone With or Without Abemaciclib in Participants With Prostate Cancer

    Scottsdale/Phoenix, AZ

  6. A Study Comparing Orteronel Plus Prednisone in Patients with Metastatic Castration-Resistant Prostate Cancer, who have not had Chemotherapy

    Jacksonville, FL, Rochester, MN

  7. Phase I Cabazitaxel, Mitoxantrone, and Prednisone Metastatic Castration-Resistant Prostate Cancer

  8. Enzalutamide With or Without Abiraterone and Prednisone in Treating Patients With Castration-Resistant Metastatic Prostate Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN, Mankato, MN, Eau Claire, WI

  9. The Role of Highly Selective Androgen Receptor (AR) Targeted Therapy in Men With Biochemically Relapsed Hormone Sensitive Prostate Cancer

  10. Rapid-Plan Knowledge-Based Planning vs. Human-Driven Planning for Prostate Cancer Radiotherapy

    Scottsdale/Phoenix, AZ

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