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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 13 for Memory

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  • Study status: Open/Status Unknown
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  1. Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss

    Jacksonville, FL, Rochester, MN

  2. A Study to Improve the Quality of Dementia Care

    Rochester, MN

  3. A Study to Evaluate CC-98633 to Treat Subjects with Relapsed and/or Refractory Multiple Myeloma

    Rochester, MN, Scottsdale/Phoenix, AZ

  4. Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases

    La Crosse, WI, Albert Lea, MN, Eau Claire, WI, Mankato, MN, Rochester, MN, La Crosse, WI

  5. Mayo Alzheimer's Disease Research Center

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. A Study to Analyze Isolation, Activation and Expansion of Mutation Reactive T-cells

    Rochester, MN

  7. Cerebrospinal Fluid (CSF) Biomarkers for Prediction of Dementia

    Jacksonville, FL, Rochester, MN

  8. Electronic Validation of Online Methods to Predict and Monitor Cognitive Decline (e-VAL)

    Rochester, MN

  9. Advanced Care Planning in Dementia

    Jacksonville, FL

  10. Imaging Dementia—Evidence for Amyloid Scanning (IDEAS) Study

    Rochester, MN, Jacksonville, FL

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