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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 521-530 of 685 for Cancer

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  • Study status: Open/Status Unknown
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  1. Integration Of Fluid Integration Of Fluid And Imaging-Based Markers For Prostate Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. International Registry For Men With Advanced Prostate Cancer (IRONMAN)

    Jacksonville, FL

  3. A Study to Evaluate Screening Contrast Enhanced Digital Mammogram (CEDM) in Study Participants at Intermediate Breast Cancer Risk and Polygenic Risk Score (PRS) Results

    Rochester, MN

  4. Screening and Staging of Benign vs Malignant Pelvic Abnormalities

    Rochester, MN

  5. Digital Biomarker And Omics-Based Assessment Of Surgical Resiliency In Children Undergoing Solid Tumor Resection

    Rochester, MN

  6. Outcomes And Patient Satisfaction For Patients Admitted To The Mayo Clinic Florida Care Hotel After Mastectomy And Tissue Expander Placement

    Jacksonville, FL

  7. A Study Of The Mechanism Of Origin In Germ Cell Tumor-associated Hematologic Malignancies

    Rochester, MN

  8. A Prospective Ocular Tumor Study

    Rochester, MN

  9. Gastrointestinal-Related Cancers and Diseases

    Rochester, MN

  10. Detection of Mutant Circulating Tumor (CT)Dna in Uveal Melanoma With Development of a Droplet Digital Pcr (Ddpcr) Assay

    Rochester, MN

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