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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 705 for Cancer

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  1. Study to Improve health-related quality of life (HRQOL) in Black Prostate Cancer Patients (CaPQoL) through Whole Person Survivorship Care

    Jacksonville, FL

  2. Acceptance and Commitment Therapy Compassion-Based Virtual Group Intervention for Diverse Cancer Patients

    Scottsdale/Phoenix, AZ

  3. A First-in-human Study of 3HP-2827 in Patients With Unresectable or Metastatic Solid Tumors With FGFR2 Alterations

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. A First-in-Human Study of BG-C137, an Anti-FGFR2b Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

    Rochester, MN

  5. Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. CJNJ-67652000 and Prednisone for the Treatment of Men With Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

    Jacksonville, FL, Rochester, MN, Scottsdale/Phoenix, AZ

  7. Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

    Rochester, MN

  8. Empty Bladder Impact During Radiation Therapy for Prostate Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Albert Lea, MN, Eau Claire, WI, La Crosse, WI, Mankato, MN, Rochester, MN

  9. NL-201 in Patients With Relapsed or Refractory Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies (ERADIC8)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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