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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 47 for (plastic OR reconstructive) AND surgery

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  1. Utilization and Storage of Liposuction Aspirate in Humans

    Jacksonville, FL

  2. A Study of Subcutaneous versus Subpectoral Placement for 2-Staged Implant-Based Breast Reconstruction

    Rochester, MN

  3. Acellular Human Nerve Allografts as a Means to Decrease Sensory Deficits following Peripheral Nerve Biopsy

    Rochester, MN

  4. A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects who are Undergoing Primary Breast Reconstruction or Revision Reconstruction

    Scottsdale/Phoenix, AZ

  5. Analysis of Thumb Carpometacarpal Pyrocarbon Arthroplasty

    Rochester, MN

  6. A Study to Evaluate the Impact of Near-Infrared Vein Mapping on Outcomes and Satisfaction After Botox/Filler Treatment

    Scottsdale/Phoenix, AZ

  7. A Study to Evaluate Treating Post-Mastectomy Radiation Injury in Breast Cancer Patients with Adipose-Induced Regeneration of Breast Skin (AIR Breast)

    Jacksonville, FL

  8. A Study of Simulated Sylvian Fissure Dissection Under Subarachnoid Hemorrhage Conditions Using a Rodent Microvascular Anastomosis Model

    Rochester, MN

  9. A Study to Assess the Effect of Pudendal Nerve Block for Postoperative Pain Control in Patients Undergoing Neo-vaginoplasty Procedure

    Rochester, MN

  10. Botulinum Toxin A (Botox) in Tissue Expander Breast Reconstruction

    Rochester, MN

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