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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 21 for

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  1. Excretion of Mast Cell Mediators in Children with Allergic Disorders

    Rochester, MN

  2. Mayo Clinic Program for the Study of Mast Cell and Eosinophil Disorders Cell and Serum Bank

    Rochester, MN

  3. Evaluation of Immunophenotype Signatures in Hypereosinophilia-Associated Disorders

    Rochester, MN

  4. Trimethoprim-sulfamethoxazole Graded Administration in Oncology, Hematopoietic Stem Cell Transplant, and Solid Organ Transplant Patients with a History of Sulfonamide Allergy

    Rochester, MN

  5. New Mast Cell Lines from Patients with Systemic Mastocytosis

    Rochester, MN

  6. Nasal Epithelial Cell Culture And Responsiveness Study

    Rochester, MN

  7. Analysis of Group 2 Innate Lymphoid Cells in Peripheral Blood

    Rochester, MN

  8. Prognostic Risk Evaluation for Hypereosinophilic Syndrome (HES) and Idiopathic Hypereosinophilia (IHE) and the Role of Next-generation Sequencing

    Rochester, MN

  9. A Study of the Effects of Preterm Birth on Lung Disease and Innate Immunity Later in Life

    Rochester, MN

  10. A Study to Evaluate the Effect of Medical Intervention on Sinonasal Inflammation in Patients with Chronic Sinusitis, Nasal Polyps and Positive Sinus Culture

    Jacksonville, FL, Scottsdale/Phoenix, AZ

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