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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 57 for Center for Regenerative Medicine

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  1. MSC for Occlusive Disease of the Kidney

    Rochester, MN

  2. A Study of a Stem Cell Fistula Plug to Treat Cryptoglandular Perianal Fistulas

    Rochester, MN

  3. A Study of the Safety of Joint Injected Sc-rAAV2.5IL-1Ra (a Virus Carried Gene Therapy) in Patients with Moderate Knee Osteoarthritis

    Rochester, MN

  4. Phase I Safety and Feasibility Study of Intracoronary Delivery of Autologous Bone Marrow Derived Mononuclear Cells

    Rochester, MN

  5. A Study of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Stage II Palliation of Hypoplastic Left Heart Syndrome

    Rochester, MN

  6. An Efficacy, Safety and Tolerability Study of Ixmyelocel-T Administered via Transendocardial Catheter-based Injections to Subjects with Heart Failure Due to Ischemic Dilated Cardiomyopathy (IDCM)

    Scottsdale/Phoenix, AZ

  7. Study Comparing NOVOCART 3D and Microfracture Surgery for Treatment of Articular Knee Cartilage

    Rochester, MN

  8. Stem Cell Fistula Plug in Perianal Crohn's Disease

    Rochester, MN

  9. Mesenchymal Stem Cell Therapy in Multiple System Atrophy

    Rochester, MN

  10. A Phase I Study of iPS Cell Generation From Patients With COPD

    Rochester, MN

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