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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 6501-6510 of 11689

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  1. Ultrasound Assessment of Weightbearing and Non-Weightbearing Meniscal Protrusion

    Rochester, MN

  2. Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

    Mankato, MN

  3. Evaluation Of RBS2418 In Combination With Tremelimumab Plus Durvalumab In Participants With Advanced Unresectable Hepatocellular Carcinoma

    Jacksonville, FL

  4. Perfusion Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty

    Rochester, MN

  5. A Study of Pre-Conditioning Prior to Surgery to Improve Functional and Clinical Outcomes in Patients with Aortic Stenosis

    Eau Claire, WI, Rochester, MN

  6. A Study of the Potential for Polyethylene Glycol (Miralax) to Metabolize into Toxic Oxalate

    Rochester, MN

  7. Evaluate how Measurements of the Cornea Correlate to the Function of the Inside Lining (Endothelium) of the Cornea

  8. Neurotransmitter Measurements Using Wireless Instantaneous Neurotransmitter Concentration System (WINCS) During Deep Brain Stimulation Neurosurgery

    Rochester, MN

  9. Corticosteroid/Ropivacaine Versus Corticosteroid/Saline Injections for Knee Osteoarthritis

    Rochester, MN

  10. A Study of Tooth Root Coverage Using a Tissue Graft for Treatment of Gum Recession from Gingivitis

    Rochester, MN

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