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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 5111-5120 of 11316

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  1. Stress Management and Resilience Training (SMART) Intervention for Family Caregivers of Individuals With Advanced Cancer

    Rochester, MN

  2. A Study to Evaluate the Efficacy and Safety of Oxabact in Patients With Primary Hyperoxaluria

    Rochester, MN

  3. Spoken Language Computational Analysis in Mania

    Rochester, MN

  4. AI based non-invasive detection of blood pressure using photoplethysmogram

    Jacksonville, FL

  5. Modified VR-CAP and Acalabrutinib as First Line Therapy for the Treatment of Transplant-Eligible Patients With Mantle Cell Lymphoma

    Rochester, MN

  6. Efficacy and Safety of Riociguat in Patients With Systemic Sclerosis

  7. Mindfulness Based Resilience Training

    Scottsdale/Phoenix, AZ

  8. A Study of the Impact of Using Barcode Scanning in Orthopedic Surgery on Patient Safety, Efficiency, and Cost

    Scottsdale/Phoenix, AZ

  9. Leukapheresis using Amicus Separator

    Rochester, MN

  10. Compassionate Use of Lorlatinib:PF-06463922 for Male Patient

    Rochester, MN

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